Systemic vasculitis is a chronic disease for which there is no clinical cure and long-term treatment is needed. Generally, comprehensive drug therapy can be used to control symptoms, slow down the development of vascular lesions and prevent complications, but the disease cannot be cured by infusion. The main method of systemic vasculitis is drug treatment, including commonly used glucocorticosteroids, immunosuppressants, biological agents and so on. 1. Glucocorticosteroids: large doses are usually used, and an infusion approach is taken in the early stage. Until the condition is relieved, then gradually reduce the dose to the maintenance dose, at this time is usually oral drugs to maintain. 2. Immunosuppressants: immunosuppressants such as cyclophosphamide can be used for infusion treatment in the acute stage, and azathioprine and methotrexate can be taken orally in the remission stage for maintenance treatment without infusion. 3. Biological agents: Some vasculitis can be treated by subcutaneous injection of TNF-α inhibitors such as adalimumab and intravenous infusion of inhibitors of interleukin 6. The appearance of systemic vasculitis should seek medical treatment in time, follow the doctor’s instructions for medication, and strive for early detection, early diagnosis and early treatment.