Vasculitis is a group of diseases in which inflammation and destruction of blood vessels are the main pathological changes, and its symptomatic manifestations can be categorized into systemic and local symptoms. In vasculitis, there are inflammatory cell infiltration in the vessel wall and perivascular area, accompanied by vascular damage. The main symptom of vasculitis is multi-system damage, which is divided into systemic and local symptoms. Most of the systemic symptoms are fever, malaise, and joint and muscle pain. Skin damage is characterized by erythema multiforme, nodules, purpura, papules, etc., with the most common being below the knees, and the most frequent skin damage on the lower part of both calves and the back of the feet. Local symptoms vary according to the blood vessels and organs affected by vasculitis. For example, aortitis mainly involves thick blood vessels, such as the thoracic and abdominal aorta, head and arm arteries, pulmonary arteries and other thick blood vessels in the human body. It can lead to fainting, cerebral infarction, pulmonary hypertension, cold claudication of the affected limbs, loss of vision, angina, etc. Nodular polyarteritis and thromboembolic vasculitis mainly involve small and medium-sized arteries, which can lead to ischemic manifestations of the tissues and organs supplied with blood, such as the involvement of the mesentery leading to mesenteric artery thrombosis, mesenteric ischemia leading to abdominal pain and so on. Kidney involvement may result in proteinuria, hematuria, and in severe cases, renal failure. Another type of vasculitis is bacterial vasculitis, which is often characterized by symptoms of thrombophlebitis, with redness, swelling, high skin temperature, and pain in the affected blood vessels. Vasculitis is not a disease, but a group of diseases, so its clinical manifestations are diverse and lack specificity.