Nephrotic syndrome (NS) can be caused by a variety of etiological factors and is a group of clinical syndromes characterized by increased permeability of the glomerular basement membrane, manifested by massive proteinuria, hypoproteinemia, high degree of edema, and hyperlipidemia. 1, nephrotic syndrome is a common chronic, recurrent renal disease in children, the course of the disease is prolonged, easy to relapse, part of the cases will become refractory nephrotic syndrome. Many patients have to turn to different doctors or even go to different doctors for a long time, or have unsystematic and irregular treatment, which leads to poor efficacy and serious complications, or serious adverse drug reactions, which brings huge economic burden and mental pressure to the children and their parents, and even affects the long-term prognosis of the children with nephrotic syndrome. 2, diagnosis and treatment of nephrotic syndrome need confidence, patience, perseverance, and establish good mutual trust with specialized medical personnel, close cooperation, the condition of the patient can be on the Internet to the specialist for consultation and communication; to adhere to the systematic, standardized, long-term formalized treatment, and regular follow-up review, timely adjustment of the treatment program; in order to achieve the ultimate common goal of the two sides of the doctor and patient: the cure of children’s nephrotic syndrome, to prevent its chronic development. To achieve the ultimate goal of both doctors and patients: to cure children’s nephrotic syndrome and prevent its chronic development. 3, nephrotic syndrome children hospitalized during the appropriate goals: clear and detailed diagnosis; formulate treatment plans; effective control or alleviation of the condition; learning, understanding of nephrotic syndrome diagnosis, treatment, prevention, care and monitoring of the condition of the relevant knowledge; prevention and treatment of possible serious adverse reactions to therapeutic drugs. 4, nephrotic syndrome children hospitalized, parents should listen carefully to the specialist’s checkups, accept the health guidance of health care personnel, and exchange with other patients experience, lessons learned and experience; to learn to observe and record the child’s urine output, urinary protein, edema, blood pressure, mental appetite and other changes in the condition; but also to train and cultivate children, especially infants and young children’s medication compliance, to ensure that the medications used The company has also trained and trained children, especially infants and young children, to comply with the use of drugs to ensure that the drugs used in practice. 5, nephrotic syndrome special treatment drugs are glucocorticoids and (or) a variety of immunosuppressants, but they have an established treatment program and course of treatment, and there are varying degrees of toxic side effects of drugs, so it should be strictly in accordance with the doctor’s instructions to regularize the use of drugs, to prevent abuse, do not arbitrarily change the use of the dosage or stop, and not a long time to adjust the amount of non-decrease, should be regular follow-up according to the plan, under the guidance of specialists according to the need for timely adjustment of drug dosage, the disease, the dosage of the drug. The dosage, usage and course of treatment should be adjusted according to the needs of the disease under the guidance of specialized doctors. Do not just count on the bedside doctor, but rely on yourself to use a special notebook to record the details of glucocorticosteroids, immunosuppressants and other special medications, including their names, dosage, start and stop time or duration of the medication, the cumulative number of times or total amount of the medication, etc., and together with the doctor to verify that the medication used is not missing, there is no omission or misuse of the medication, and there is no prolonged use of the medication without adjustments (it should be understood that the doctor can not remember every patient’s name or dosage: Doctors cannot remember every patient’s previous medication details). 6, a variety of infections and allergic diseases are the primary cause of recurrence of nephrotic syndrome. Throughout the course of the disease (including after discharge from the hospital and after the urine protein turns negative) should strengthen the care, prevention and treatment of colds, infections, to prevent mosquito bites and allergic diseases (to fully understand: prevention is more important than treatment); to pay attention to the removal of various cavities parts of the hidden foci of infection (eg, pharyngitis, tonsillitis, gingivitis, rhinitis, sinusitis, otitis media, etc.); to minimize the number of visitors in the wards, regular disinfection, keep home air fresh, and keep the home air fresh, so as to minimize the number of patients with nephrotic syndrome, and to reduce the number of patients who have to be treated. Disinfection, keep the air at home fresh, try to avoid going to crowded public places; to adhere to long-term salt water gargling (at least 2 times a day), try to avoid eating frozen food, less snacks; adhere to the long-term use of immunomodulators; vaccination should be weighed against the pros and cons of the prudent, so as not to lead to relapse of nephrotic syndrome. When there are signs of infection, effective treatment should be timely. 7, on the rest and activities: in addition to significant edema, severe hypertension or complications of obvious infections, children should be encouraged to appropriate light activities, should not be long bed rest. 8, about diet and salt: the use of glucocorticosteroids in children, it is advisable to eat more fruits, vegetables, control high protein, high-fat food, intake of appropriate amount of high-quality protein. In addition to significant edema, severe hypertension and sometimes short-term term salt, should be encouraged to try to normal salt diet, never a long time low-salt, or even no salt diet. 9. About Chinese herbal medicine and secret prescription: Encourage the combination of Chinese and western medicine, but do not advocate the blind use of Chinese herbal medicine of unknown origin or unclear prescription and secret prescription, in order to avoid the occurrence of Chinese medicine nephropathy or affect the regular treatment of nephrotic syndrome and long-term efficacy of the use of Chinese herbal medicine and secret prescription.