Cough and fever in adults can be caused by a variety of reasons. The specific medication needed depends on the cause of the cough and fever, and treatment should be directed at the cause. If the illness is short-lived and accompanied by symptoms such as nasal congestion, sneezing, runny nose and sore throat, it belongs to upper respiratory tract infection, which is mostly caused by viral infections, and can be treated with oral medications such as Shuanghuanglian Oral Liquid and Lianhua Qingfei Capsules to clear heat and detoxify toxins. If the fever persists and the patient coughs up purulent sputum, it is considered to be combined with bacterial infection. In addition to oral cough and sputum treatment, oral antibiotics such as cephalosporins, penicillins or quinolones are also needed for anti-infection treatment. If the patient’s cough and fever are heavy and oral medication is not effective, he or she can go to the hospital and have a chest X-ray or CT taken to see if patients with lower respiratory tract infections such as pneumonia and bronchiectasis require intravenous antibiotic anti-infection treatment.