Patients who are ineffective after regular treatment or repeatedly deteriorate should be highly suspected of having drug-resistant tuberculosis and sent for drug sensitivity testing in a timely manner to adjust the treatment regimen.
Drug-resistant tuberculosis can be classified as
Mono-drug-resistant TB disease That is, Mycobacterium tuberculosis isolated and cultured from the patient’s sputum or other body fluids is resistant to one first-line anti-tuberculosis drug (such as isoniazid, rifampin, pyrazinamide, ethambutol, streptomycin). Bai Xuepeng, Department of Thoracic Surgery, Shandong Provincial Chest Hospital
Multi-drug resistant tuberculosis (MDR-TB) means isolated and cultured Mycobacterium tuberculosis that is resistant to multiple first-line anti-tuberculosis drugs, but not both isoniazid and rifampin.
Multidrug-resistant tuberculosis (MDR-TB) refers to isolated and cultured Mycobacterium tuberculosis that is resistant to at least two or more drugs, namely, isoniazid and rifampin.
Severe multidrug-resistant tuberculosis (XDR-TB) refers to isolated and cultured Mycobacterium tuberculosis that is resistant to not only isoniazid and rifampin, but also all fluoroquinolones and one second-line injectable drug.