Ejaculation usually means that although the penis can have normal erection and intercourse, it just cannot reach orgasm and obtain sexual pleasure, and cannot ejaculate semen. Ejaculation is distinguished from retrograde ejaculation, which is the absence of semen and sperm from the urethra, but the presence of orgasm and the feeling of ejaculation. Ejaculation is divided into two categories: organic and functional ejaculation. Organic ejaculation includes congenital abnormalities in gonadal development or genital anatomy, nerve conduction disorders caused by surgery or injury, and medication (antipsychotic, antidepressant, antihypertensive and sedative drugs, etc.) factors. Most of the common clinical cases are functional non-ejaculation caused by psychological factors, such as non-ejaculation in the vagina and ejaculation of semen in other situations. Common causes of functional non-ejaculation include lack of sexual knowledge, sexual fear, sexual disharmony, and insufficient sexual stimulation. Functional ejaculation is usually cured by psychological and behavioral treatment, Chinese and Western medicine treatment or electric massage treatment, and can be cured by ejaculation in the vagina through sexual intercourse, thus not affecting fertility. For patients with organic ejaculation or those who have been treated ineffectively, assisted reproductive technology can be used to achieve the goal of fertility. For example, for patients who do not ejaculate during sexual intercourse but can ejaculate by masturbation, sperm can be obtained by masturbation during the wife’s ovulation period and intrauterine insemination treatment can be performed. For patients who are unsuccessful in all methods, sperm can be collected from the epididymis or testes for ICSI treatment.