Patient: June:ALT:345.AST:260. AST: 870, virus: five. Small triple yang medication: Yuzhomycin. Why is the ALT high, is Überallergen effective? This is an effective performance. It is also a normal phenomenon and often indicates that satisfactory results may be received. That is because while interferon is fighting the virus and clearing it, the liver cells infected with the virus are simultaneously attacked and damaged. However, your case seems to be delayed a little bit, and the ALT and AST seem to be a little bit higher, which is an acceptable height if there is no jaundice. There is no need to worry too much, but you should review regularly, and at the same time you can supplement with some liver-protective drugs, and pay attention to rest to avoid too much liver damage. If liver function deteriorates further, you should see a physician at the hospital in time. Zhou Ping, Department of Infectious Diseases, Air Force General Hospital Patient: On June 17, he used Yuzhosin and his ALT was 345 and DNA was 7. On August 25, his ALT was 59 and DNA was 7. On September 5, he had a headache and bitter mouth and ate less, and on September 10, his ALT was 1120 and DNA was 5. He is now hospitalized. I stopped using pertussin to protect my liver. If the ALT drops to 50, I can stop using worry about it if I maintain a small triplet, right? If I add liver-protective medication along with the worry factor, the ALT will not be too high. But the damage to the liver is the same, isn’t it? Maybe that’s what happens when you go from a major triplet to a minor triplet in two months or so, I’m taking a shot of Zyrexin every other day, so if it’s three times a week, it’s better. Maybe four times in ten days is better. I think these details are very important to deal with. My liver is actually damaged, but the bilirubin is low. Patient: 1. I think the Überallergen is ostensibly effective, but it’s actually very difficult in terms of controlling the dosage, and it’s easy to do a lot of damage to the liver. I think if I am three times a week. 300 IU each time is good, I used to be 500 IU. 2, I have stopped taking ursodiol for a week, I want to take ursodiol again next week, I now take 500 each time, twice a week is good, or each time take 300, three times a week is good? 3. How long should I do it again? How much of the virus can be stopped if the minor triad is maintained well. I use a2b (Intron) Air Force General Hospital, Department of Infectious Diseases, Zhou Ping: ALT is rising too fast, is there any other reason? Such as co-infection with other types of hepatitis, hepatitis A or E? Or drinking alcohol? Taking other drugs? And so on. If it can be excluded, still should consider the factor of interferon, may be more sensitive related, such as continued use, it is recommended that each time 3 million units, 3 times a week, pay attention to monitor the blood, liver function, virus and other index changes during the use. If the efficacy is good, the liver function should gradually will be normal, the virus negative (undetectable), and continue to maintain a small triplet. The best result is a negative HBsAg. Patient: Thank you. I will agree on whether to give dry worms after another lab test this Friday. I think the rise in ALT is the effect of interferon. My question is: enzyme lowering drugs affect the disease observation, can I ask not to lower the enzyme . Zhou Ping, Department of Infection Medicine, Air Force General Hospital: If you continue to use interferon treatment, you may not use enzyme-lowering drugs in order to observe the efficacy of interferon, but you should pay attention to the changes in liver function. If you do not use interferon, you should preserve the liver and lower the enzymes. Allow liver function to recover. Patient: Thanks a Am I immune overstimulation? I think there are two ways to prove it: 1, dry worms dosage is reduced and observed. 2, without lowering the enzyme, whether ALT rises II, whether to request a mutation test. Zhou Ping, Department of Infection Medicine, Air Force General Hospital: It is recommended to reduce the dosage of interferon and closely observe the changes in liver function and viral indicators. What is the mutation test you are referring to? If it is a viral mutation test, applying interferon treatment, I think it is not necessary to do. If it is in the process of applying nucleoside analogues such as: lamivudine, adefovir, etc., your situation may suggest the existence of viral mutation, the emergence of drug resistance, etc. Tests can be performed. Patient: Yes, it is not necessary to do it, I understand.