Abdominal distension and shortness of breath and chest tightness may be caused by heart disease or gastrointestinal disease, which can be treated by lifestyle modification, drugs such as nitroglycerin, omeprazole, thioglycollate, and interventional therapy. 1. Heart disease: such as myocardial ischemia, hypertension and other diseases, will lead to chest tightness, shortness of breath, and at the same time, the stomach will be distended and other discomfort. Need to pay more attention to rest, keep the mood optimistic, and follow the doctor’s instructions to use medication, such as nitroglycerin, sodium nitroprusside, spironolactone, etc., if necessary, give oxygen inhalation, and in severe cases, give the internal medicine interventional therapy. 2. Gastrointestinal diseases: such as dyspepsia, acute and chronic gastritis, gastroesophageal reflux and other diseases, will also appear bloating, shortness of breath, chest tightness and other symptoms. It can be treated by adjusting daily diet structure and using acid-suppressing drugs as prescribed by doctors, such as omeprazole, cimetidine, etc.; and gastric mucosa-protecting drugs, such as bismuth potassium citrate, aluminum thioglycollate, etc.. If the symptoms of abdominal distension, shortness of breath and chest tightness have not been relieved, the patient needs to go to the hospital in time for treatment.