Acne is a pre-acne lesion, divided into whiteheads (closed pimples) and blackheads (open pimples), the former for the yellow sebaceous keratin, while the latter is oxidized sebaceous plugs; 50-year-old men also long acne, may be due to endocrine disorders or irregular work and rest. 1. endocrine disorders: if the body hormone imbalance may lead to endocrine disorders, which will appear folliculitis, acne, due to the follicle sebaceous gland openings keratinization blockage, sebum content is not easy to discharge, blockage accumulation and the formation of pimples. 2. Irregular work and rest: If you don’t pay attention to the diet, often stay up late and tired, lack of sleep, the body’s immune system decline and other factors, for a long time will cause the symptoms of endocrine disorders in the body, thus triggering the production of acne. If you are 50 years old and still have acne, it is recommended to go to the hospital for examination, after the doctor’s diagnosis, to clarify the cause of the standardized treatment.