Some drugs and substances are damaging to human hearing, I will briefly list the ototoxic substances: 1, aminoglycoside antibiotics. 2, certain anti-tumor drugs, such as cis-chloroplatinum, nitrogen mustard, and contraxin, etc. 3.Salicylic acid preparations. 4.Quinine. 5.Tab diuretics. 6.Local anesthetics, such as lidocaine, cocaine, etc. 7, heavy metals, such as lead, cadmium, mercury. 8.Inhalation of harmful gases, such as carbon monoxide, hydrogen sulfide, aniline, etc. 9, cardiovascular drugs, hypoglycemic drugs, tranquilizers and vancomycin and polymyxin, etc. 10, proprietary Chinese medicines, such as Niuhuang Qingxin Pill, Qi Zhen Dan, etc.