1. Genetics. There is a clear family history to consider eugenics or infertility issues. 2, consanguineous marriage. Resolutely eradicate, if already married, must not have children. 3, ototoxic antibiotics problem. Avoid the use of ototoxic antibiotics such as streptomycin, neomycin, kanamycin, etc. 4. Hyperthermia in infants and children. Continuous high fever may cause serious damage to the child’s hearing. 5, newborn hearing screening is very important, for the first screening failed, must be reviewed after 6 months, for no response to any external loud sound, because early to go to a specialist consultation and examination.