Can you skip chemotherapy after colon cancer surgery?

Early stage colon cancer can be treated without chemotherapy after surgery. early stage colon cancer refers to stage I colon cancer, including T1N0 and T2N0. T1N0 refers to tumor invasion in the mucosal layer and no surrounding lymph node metastasis, so chemotherapy is not needed. T2N0 refers to tumor invasion in the mucosal layer and submucosal layer without surrounding lymph node metastasis, so chemotherapy is usually not needed. However, it depends on whether the tumor has high-risk factors, i.e., whether the tumor is hypodifferentiated or undifferentiated adenocarcinoma, whether there is vascular invasion or nerve invasion. If there are high-risk factors, it is recommended to take oral chemotherapy as a single agent, such as capecitabine.