There are more than 9 million people with epilepsy in China, and nearly half of them are female patients. After pregnancy, the internal environment of the body changes, often leading to worsening seizures. Both the epileptic seizures themselves and the long-term use of antiepileptic drugs (AEDs) can affect the pregnant woman, and can even cause abnormal fetal development. Therefore, how should people with epilepsy cope with pregnancy and minimize the impact on the fetus? A. Pregnancy in patients with epilepsy should be planned. For patients with epilepsy who plan to become pregnant, if the seizures are effectively controlled and it is possible to stop the medication, it is recommended to consider planning pregnancy six months after stopping the antiepileptic drugs; if it is not possible to stop the antiepileptic drugs and plan pregnancy, it is recommended to adjust the antiepileptic drugs to a low dose of monotherapy as much as possible, and attention should be paid to folic acid supplementation because antiepileptic drugs can lead to folic acid deficiency. Second, patients with epilepsy should choose antiepileptic drugs that have less impact on the fetus during pregnancy as much as possible, and a single drug at a low dose that can control seizures is best to avoid polypharmacy. It is currently believed that newer antiepileptic drugs such as lamotrigine and oxcarbazepine have a lower teratogenic rate, while traditional antiepileptic drugs such as sodium valproate and phenobarbital have a higher teratogenic rate. In addition, physiological changes during pregnancy can affect the pharmacological metabolism of antiepileptic drugs, so patients with epilepsy taking traditional antiepileptic drugs should regularly monitor their blood concentration and adjust the drug dose in combination with seizure conditions and adverse drug reactions. Third, patients with epilepsy should develop good lifestyle habits, ensure adequate rest, avoid seizure triggering factors such as smoking, alcohol and coffee, and also increase the number of prenatal checkups during pregnancy. In summary, patients with epilepsy should plan their pregnancy, receive guidance from a professional physician throughout the process, and conduct pregnancy examinations closely.