If patients often have chest tightness and dyspnea while sleeping: 1. First of all, we should consider respiratory diseases, such as chronic bronchitis, chronic bronchiectasis, chronic obstructive pulmonary emphysema, pulmonary hypertension, pulmonary heart disease, asthma, all of these conditions will cause low partial pressure of oxygen and high partial pressure of carbon dioxide, which will trigger chest tightness, shortness of breath and dyspnea for a long time; 2. Patients with the above conditions have a history of cardiogenic diseases in These conditions will lead to ischemia, stenosis and spasm of the coronary arteries, causing insufficient blood supply and oxygen supply to the cardiac muscle cells, and therefore chest tightness and dyspnea when sleeping; 3, for patients with cardiac neurosis, they will also have this condition when they have plant nerve dysfunction 4, in addition, for endocrine metabolic diseases, such as thyroid dysfunction and adrenal cortical dysfunction, there will also be such clinical manifestations.