Currently, the most common treatment for hepatitis C is a combination of long-acting interferon + ribavirin. Ribavirin is an oral drug, while interferon needs to be injected intramuscularly to work. In addition, oral small molecule antiviral drugs have been developed abroad in the last two years, which is a good option for patients who cannot use interferon. Different virus genotypes have different treatment times and different effects! For patients with type I hepatitis C, long-acting interferon + ribavirin for at least 48 weeks of treatment. For other types of patients, long-acting interferon + ribavirin for at least 24 weeks. The results will be relatively better if the duration of treatment is extended appropriately. Therefore, before antiviral treatment, patients need to be checked for genotyping of the hepatitis C virus. The duration and effectiveness of treatment varies depending on the genotype. Some patients do not check before treatment, playing on the interferon on the virus is not unable to typing, can only play according to a long course of treatment, in order to avoid prolonging the medication (more interferon), patients must check the genotyping before treatment. This will not only reduce the side effects of interferon, but also reduce the financial burden of the patient. In addition to this, what other tests are required before taking interferon? The main tests include liver ultrasound, electrocardiogram, chest X-ray, autoantibody tests (interleukin 28, IL-28), thyroid function tests and tests needed for the evaluation of pre-existing diseases. Liver ultrasound is done mainly to check the inflammatory status of the liver, assess the degree of development of hepatitis C, and determine whether there is fibrosis, decompensated cirrhosis, etc. If the liver ultrasound results show severe cirrhosis, interferon cannot be administered. In patients with cirrhosis, the risk of interferon administration is greatly increased and the benefits are limited, and oral small fractionated sub-drugs such as sofosbuvir are preferred at this time. Other tests are done to rule out other serious diseases other than the liver, such as serious autoimmune diseases, heart disease, renal insufficiency, etc. Patients who have these diseases should not use interferon as it will worsen the symptoms of these diseases. In addition, people who have serious mental illnesses (such as severe depression, etc.), have had transplants of organs other than the liver, and are pregnant are also not suitable for interferon shots. Therefore, before taking interferon, make sure to consult a professional doctor at a regular hospital, don’t hide your condition in order to be sure to take interferon, and cooperate with your doctor to complete the relevant tests.