Patients with congenital heart disease can have their hearts transplanted. Generally, heart transplantation is aimed at patients with end-stage congenital heart disease that cannot be cured by various methods such as surgery and intervention and whose life expectancy does not exceed six months or one year. In contrast, most patients with congenital heart disease can achieve a very satisfactory result after treatment with open surgery. For complex types of congenital heart disease, the results of heart transplantation are also quite good when conventional surgical treatment is not effective. At present, heart transplantation for congenital heart disease in our country is often performed on pediatric patients, infants or children, because congenital heart disease is less reactive and less medicated after heart transplantation, and the results are better than those of adults. However, one of the biggest uncertainties in children after heart transplantation is the poor compliance of children and parents with follow-up medications. Some people feel that everything is fine after surgery and that they don’t need to take medications, so they stop taking them without permission, which can cause rejection and even death. There are very many successful experiences, but the failure is also very painful once it happens. If you follow the doctor’s strict requirements for review, the surgical results should be better than the adult results.