Patients with lumbar spondylolisthesis are usually treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and neurotrophic drugs. 1. Patients with lumbar spondylolisthesis usually have symptoms of low back pain, and patients can use non-steroidal anti-inflammatory drugs, such as celecoxib, to relieve pain symptoms. 2. Patients may also be due to lumbar spondylolisthesis compression of the spinal canal, resulting in nerve edema, it is recommended that patients take some drugs that can be used to nourish the nerves, such as B vitamins, methylcobalamin tablets and other drugs. 3. It should be noted that patients with severe lumbar spondylolisthesis can not solve the symptoms only through medication, and need to undergo lumbar spondylolisthesis surgical treatment to restore the normal lumbar vertebrae structure and relieve the symptoms of spinal canal compression. The above drugs need to be used under the guidance of a doctor.