Whether lower extremity venous thrombosis will be amputated depends on the specific situation; if the patient’s symptoms are not serious and timely treatment, amputation is not necessary; if the patient’s symptoms are serious and the disease is delayed, amputation may be required. If the patient’s symptoms are not serious, timely medical treatment, thrombolysis, anticoagulation and other drug therapy under the guidance of the doctor; if necessary, especially for the central or mixed lower extremity venous thrombosis patients, should rule out contraindications to surgery, timely surgery to remove the embolism treatment, the patient’s general prognosis is good. If the patient’s symptoms are serious and the diagnosis is late, the condition is delayed, and also belongs to the central type of venous thrombosis, at this time, it will have a serious impact on the patient’s lower limb blood flow, if the treatment is not timely, may need to amputate the limb. When venous thrombosis occurs in the lower limbs, it is necessary to consult a doctor in a timely manner and carry out standardized treatment under the guidance of the doctor in order to avoid delaying the condition.