1.Sensory impairment Because the cavity most often starts from the base of the posterior horn of the cervical expansion on one side, the early prominent symptom is segmental dissociative sensory impairment, i.e., loss of pain and temperature sensation and the presence of touch and deep sensation. Most cases start with asymmetric unilateral sensory loss. Sensory loss may be reflected by painless skin ulcers, scarring, edema, Charcot joints, and resorption of the terminal finger (toe) bones. Children are most often seen with painless sensation in the fingers and localized skin burns. When the cavity expands into the anterior gray joint, bilateral “vestigial” dissociative sensory deficits appear. Sometimes the child complains of spontaneous and indescribable burning pain in the area of sensory loss, which is persistent and called “central pain”. If the cavity continues to expand and invades the thalamic tract of the spinal cord, the pain and temperature sensation below the damage plane will be lost; the posterior cord of the spinal cord is often invaded last, and deep sensory loss below the damage plane will occur. 2, motor disorders Spinal cord cavitation mostly appears in the upper limbs of the lower motor neuron atrophy and weakness. The lesions often involve the ends of the upper extremities, most often the clawed hands, and rarely affect the forearm and upper arm, with muscle atrophy and muscle bundle tremors in the corresponding segments. If the cavity is in the cervical expansion area, the small muscle atrophy of both hands is most prominent, and the tendon reflexes of the upper limbs are reduced or even absent. The upper motor neurons below the plane of damage are damaged when the pyramidal tract is invaded, and spastic paralysis of the ipsilateral limb is observed. The involvement of the T1 segment often leads to ipsilateral Horner’s syndrome. Sometimes the symptoms can be rapidly worsened by the combination of hemorrhage in the spinal cord cavity. 3, nutritional disorders Most common joint enlargement, joint surface wear, bone cortical atrophy and bone decalcification, mostly invade the upper extremity joints, not accompanied by pain, with a ringing sound when moving. Neurogenic joint lesions are called Charcot joints. In addition, the skin is dystrophic, including abnormal sweating, bruising, hyperkeratosis, and thickening of the skin. Because of the absence of pain, the fingers or toes are often injured and form stubborn ulcers, and even painless necrosis and loss of the ends of the fingers and toes, forming Morvan’s sign. 4, medulla oblongata symptoms Medulla oblongata cavernosa is mostly accompanied by spinal cavernosa, which is a continuation of spinal cavernosa. The symptoms are asymmetrical. If one side of the medulla oblongata is involved, there may be unilateral signs such as dysarthria and dysphagia; if the trigeminal spinal tract and spinal tract nucleus are involved, there may be crossed sensory impairment and fibers of cerebellar pathways are involved. 5.Other The disease may have bladder and rectal dysfunction in the late stage. In addition, the disease is often combined with a variety of congenital malformations, such as cervical ribs, high arched palate, lordosis or scoliosis of the spine, spina bifida and Arnold-Chiari malformation, bowed feet and so on. The presentation varies from patient to patient.