HPV16 is a type of human papillomavirus. High-risk HPV16+ positive is an infection of the body’s genital tract with high-risk human papillomavirus, which is more likely to cause cervical cancer, condyloma acuminatum, vaginal cancer, penile cancer, and other diseases, so high-risk HPV16+ positive is a relatively serious infection. It is usually recommended that HPV16+ positive patients undergo colposcopy 3-7 days after menstrual cleansing and take cervical biopsy during colposcopy for pathologic examination to find out whether cervical epithelial cells are lesioned under high-risk HPV infection.1. Cervical epithelial low-grade lesions: If cervical epithelial cells are lesioned at low-grade level in HPV16+ positive patients with older age, it is usually recommended to choose cervical Liposuction to treat the cervical epithelial cells. It is usually recommended to choose the cervical Lipo surgery for treatment, after the operation, but also under the guidance of the doctor to take drugs to improve immunity or antiviral drugs, regular review; 2, cervical epithelial high-level lesions: usually through the Lipo or cold knife conical dissection for pathology to clarify the diagnosis, and if the situation is more serious may need to consider whether to choose the total hysterectomy. High-risk HPV16+ positive is relatively more serious, it is recommended that the patient choose a regular hospital obstetrics and gynecology department for examination and confirmation, and under the guidance of the doctor to choose the appropriate program to actively cooperate with the treatment. Usually it is recommended to carry out a joint screening HPV, TCT again in six months, if HPV16 turn negative, but also need to be checked again in 3 months, if still negative status, the follow-up can be considered once a year check. Patients should also pay attention to rest, avoid exertion, eat a balanced and light diet, do not often eat barbecue, fried food, with appropriate exercise, such as jumping rope, running and so on.