Definition: Somatoform disorders are a group of neurological disorders characterized by a persistent fear or belief in a dominant concept of various somatic symptoms. Patients have repeatedly sought medical attention for these symptoms, and various negative medical tests and physician explanations have failed to dispel their doubts. It is often accompanied by anxiety or depression. Although the onset and persistence of symptoms are often closely related to unpleasant life events, difficulties or conflicts, patients often deny the presence of psychological factors. They also refuse to explore the possibility of a psychological etiology, even when there is significant depression and anxiety. Prevalence: Gureje et al. reported that a survey of 14 countries using the ICD-10 diagnostic criteria found that 2.8% of subjects had somatization disorder, and that 16.7% of primary care and general hospital visits were for somatoform disorders. The most common symptoms are gastrointestinal discomfort (e.g., pain, hiccups, acid reflux, vomiting, nausea, etc.), abnormal skin sensations (e.g., itching, burning, tingling, numbness, soreness, etc.), skin spots, sexual and menstrual complaints are also common, and significant depression and anxiety are often present. Multiple symptoms may coexist. Patients have undergone many tests for this purpose, with no positive findings, and even surgical exploration has yielded nothing. The course is often chronic and fluctuating, with severe and long-standing impairments in social, interpersonal and family behavior that rarely resolve completely. Causes: Somatoform disorders have complex causes that are related to genetic qualities, personality bases, physiology, psychology and many other factors. Studies have shown that the symptoms of patients with somatoform disorder are significantly and positively correlated with scores on the MMPI factors of hypochondriasis, psychopathy, paranoia, neurosis, schizophrenia, hypomania, and social introversion, indicating that there is a personality basis for the development of somatoform disorder. These personality traits have a significant driving effect on somatoform disorder patients’ worry about their somatic symptoms and repeatedly seeking help from physicians. For example, personality traits such as neuroticism, avoidance of harm, preoccupation with physical symptoms or ego may enhance patients’ experience of somatic symptoms; personality traits such as mistrust and irritability often lead patients to repeatedly seek medical help because they are dissatisfied with or even resent the current physician’s diagnosis. Treatment of patients with somatoform disorders is difficult and is mostly carried out by a combination of medication and psychotherapy.