In the course of our work, we often encounter patients who have had simple endometrial hyperplasia a year or two ago and have been treated strictly according to the doctor’s orders, only to have menstrual disorders again within six months and a year after stopping treatment, and then have simple endometrial hyperplasia on scraping, or even complicated or atypical hyperplasia. Other patients start complaining about this endometrial hyperplasia as soon as they sit in front of the consultation table, and they have scraped it four or five times, but it is still not good. So, how can endometrial hyperplasia be prevented? Generally, after endometrial hyperplasia has been effectively treated, the prevention process should be initiated. Women with fertility requirements For women with fertility requirements, promoting effective ovulation of the ovaries is the best preventive measure. It is recommended to visit a reproductive endocrinologist for assisted fertility treatment, such as ovulation promotion therapy. Even if the endometriosis is treated, if effective measures are not taken to promote ovulation, the ovaries usually will not ovulate on their own and the chances of conceiving on their own are very low. For women without fertility requirements, the preventive measure is to ensure effective progesterone protection of the endometrium. There are a number of measures available for patients to choose from depending on their situation: 1. Periodic oral contraceptives, such as Mafron. The benefit of cyclic oral contraceptives is that they ensure regular menstrual flow and allow the endometrium to peel off regularly, providing effective protection. At the same time, oral contraceptives inhibit ovulation, which is effective for contraception and allows the ovaries to get sufficient rest, with the expectation that after 3-6 cycles of use and discontinuation of the pill, ovarian function can be restored and ovulation can resume. The disadvantage is that each menstrual cycle has to be taken for 21 consecutive days, which is troublesome. Some patients have an increased appetite and weight gain after taking the medication. In addition, it is not suitable for patients with problems such as cardiovascular disease, smoking, breast disease, and tendency to thrombosis. Patients with uterine fibroids, generally oral contraceptives do not have much effect on fibroids, but they should be followed up closely. 2.Post-progestin half-cycle treatment. Taking progestin for 10 days in the second half of the menstrual cycle is the same as the progestin treatment for simple endometrial hyperplasia. The advantages and disadvantages are similar to those of oral contraceptives, but ovarian ovulation is not inhibited. 3. Endometrial removal. A more radical treatment is the hysteroscopic removal of the functional layer of the endometrium, with no postoperative menstrual flow and the concomitant irreversible loss of reproductive function. It is indicated for patients who do not have a fertility requirement and are not suitable or do not wish to take medication for prophylaxis. However, it should be noted that endometrial removal may not be able to remove all the functional endometrial layer at one time, and there may still be some endometrial growth and menstrual flow after surgery, which requires re-operation or close follow-up. 4.Close follow-up observation. Some patients are unwilling to use any of the above preventive measures because of various comorbidities or some other self-reasons. In this case, patients are required to closely observe their menstruation. If there is no menstruation beyond the normal menstrual cycle, or if the amount of menstruation is sometimes high and sometimes low, or if the menstrual cycle is sometimes long and sometimes short, it is necessary to go to the hospital in time to see a doctor.