Hypoglycemia in epileptic-like seizures presents as a shallow comatose state with moist, cyanotic skin, foaming at the corners of the mouth, upward gaze of the eyes, loss of light reflex in both pupils, neck tonicity, coarse breath sounds in both lungs, and strong heart sounds. The examination of this disease includes rapid glucose determination in patients with unexplained impairment of consciousness (or epilepsy). 1, fasting plasma insulin and glucose determination: non-obese people with fasting insulin levels higher than 24 μU/ml can be considered hyperinsulinemia, however, sometimes fasting insulin values even if normal, the relative blood glucose values have increased, when fasting blood glucose is lower than 2.8 mmol/L, plasma insulin should be reduced to less than 10 μU/ml, plasma glucose levels lower than 2.2 mmol/L, insulin values will Below 5μU/ml, the insulin to glucose ratio (I:G) is generally also reduced, if the I:G value increases or >0.3 hyperinsulinemia should be suspected, I:G>0.4 suggests the possibility of insulinoma. 2, oral glucose tolerance test (OGTT): to determine whether there is fasting hypoglycemia, OGTT is not meaningful, such as glucose tolerance test extended to 4-5h, for the diagnosis of postprandial hypoglycemia has some value. 3.Plasma insulinogen and C-peptide determination: normal plasma contains a small amount of insulinogen, and most insulinoma patients have increased insulinogen levels in the blood circulation. Under normal circumstances, insulinogen generally does not exceed 22% of total immunoreactive insulin, while the percentage of insulinogen in more than 85% of insulinoma patients exceeds 25%.