Recently, as long as the slightest exertion, Auntie Wang’s chest will be stuffy and painful, and she has to sit down and take a break to relieve it. She was afraid that she had coronary heart disease, so she rushed to the hospital for a checkup, but the CT and ECG showed no problems. Could it be that the investigation was not accurate? The family accompanied her to another hospital for tests, but the results were similar. Seeing the chest problems from time to time, Auntie Wang can no longer sit still. It is said that coronary heart disease is terrible, this person said no, and their chest pain is not found, is it a strange disease than coronary heart disease is terrible? Thinking that they are only fifty this year, the little granddaughter is still small, the tears …… later Wang aunt was diagnosed with heart X syndrome, so what kind of disease is it? Cardiac X syndrome Generally speaking, chest pain after exertion, relieved after a few minutes, appears to be a typical manifestation of exertional angina, cardiac imaging can see cardiovascular stenosis, plaque and other manifestations. However, X heart syndrome is characterized by recurrent episodes of chest tightness and chest pain, normal coronary angiogram or coronary CT, and positive exercise plate test. In other words, patients with this disease repeatedly feel chest pain, chest tightness and other discomfort, all of which can occur during exertion and quiet rest, sometimes lasting a few seconds or up to several hours, and are mostly seen in post-menopausal women. However, a coronary angiogram or coronary CT examination at the hospital indicates that the heart vessels are open and there are no lesions such as cardiovascular stenosis caused by atherosclerotic plaques due to dyslipidemia. And after increasing certain exercise load, the electrocardiogram reflects certain manifestations of myocardial ischemia. The medical diagnosis of this disease is cardiac X syndrome. Since it is not caused by dyslipidemia or atherosclerotic plaque in the large blood vessels of the heart, cardiac X syndrome must have its unique etiology. It turns out that it is a problem with the microvasculature of the heart (less than 200 microns in diameter). Currently, the most widely recognized pathogenesis lies in the abnormal structure and function of the patient’s cardiac microvasculature and its microcirculation. With such tiny vessels, it is no wonder that they are invisible on CT and imaging. What should I do if I develop similar symptoms? Although cardiac X syndrome is not serious, chest pain and chest tightness are not exclusive to it. Many dangerous diseases manifest as chest pain, such as coronary heart disease, heart attack, gastroesophageal reflux, esophagitis, esophageal cancer, lung cancer, pleurisy, etc. Therefore, adequate physical examination should be completed with the symptoms of chest pain to clarify the cause to avoid the disease from slipping through the fingers and becoming a major problem.