The cause of high blood pressure not going down needs to be clarified, for high blood pressure not going down is considered refractory hypertension, first of all, the factors of secondary hypertension should be excluded, and secondary hypertension can be treated by medication and, if necessary, surgery for radical treatment. In addition, for hypertension does not go down need to give comprehensive treatment measures, which refractory hypertension refers to the use of three antihypertensive drugs, which must include diuretics, so for hypertension does not go down need to clarify the application of diuretics in its antihypertensive program. If not, it is necessary to increase diuretics and monitor ambulatory blood pressure to clarify the type of blood pressure fluctuation, and adjust the type, duration and dosage of antihypertensive drugs according to the type, and pay attention to the improvement of therapeutic lifestyle.