Atrophic gastritis, also known as chronic atrophic gastritis, is a type of chronic gastritis. It is a chronic digestive disease characterized by atrophy of the epithelium and glands of the gastric mucosa, a decrease in number, thinning of the gastric mucosa, thickening of the mucosal base, or with pyloric glandular hyperplasia and intestinal glandular hyperplasia, or with atypical hyperplasia. There is no effective treatment for atrophic gastritis, which is mainly symptomatic. Treatment includes the following modalities: Treatment principles: The treatment goals for chronic atrophic gastritis CAG are to delay or stall the progression of lesions, reduce the risk of cancer, and improve the clinical symptoms of patients. 1. General treatment: Patients with CAG should have a regular diet with more fresh vegetables and fruits, a high-quality protein diet, a light, low-salt diet, and less or no pickled, smoked and fried foods. Establish a good doctor-patient relationship, educate patients on science, maintain an optimistic attitude, correctly understand the risks of CAG, and improve the compliance of monitoring and follow-up. 2. Improve gastric mucosal inflammation: delay progression For Hp-positive patients, eradication therapy is still the most basic treatment for CAG and enterolization eradication of Hp can reverse or slow down the progression of atrophy. A quadruple therapy consisting of bismuth + PPI + 2 antibacterial drugs is recommended. Supplementation of folic acid, vitamin C, can be used as CAG to prevent gastric cancer. 3.Symptomatic treatment can be used according to patient’s symptoms: digestive enzyme preparation, etc. For those with epigastric fullness, nausea or vomiting as the main symptoms, prokinetic drugs can be used, while those with bile reflux can apply prokinetic drugs and/or gastric mucosal protective agents with bile acid binding effect; those with obvious indigestion symptoms such as eating-related bloating and poor appetite can consider applying digestive enzyme preparations; for epigastric pain and acid reflux, PPI, H2 receptor blockers or gastric acid neutralizing drugs can be moderately used; those with mental Psychological factors, sleep disorders or those with obvious psychiatric factors, those with ineffective conventional treatment and poor efficacy can consider psycho-psychological treatment to eliminate or relieve patients’ psychological stress as well as symptomatic treatment of clinical symptoms, which has certain significance in improving prognosis. 4, according to the basic theory of Chinese medicine specific identification: at the same time according to the history of symptoms, endoscopic pathology and laboratory test results to identify the disease, clear each patient’s gastric mucosal lesions and pathophysiological changes, the disease and evidence together for individualized combined Chinese and Western medicine treatment Then, the above is the treatment of atrophic gastritis, should be under the guidance of clinicians for regular and reasonable treatment.