Congenital heart disease (congenital heart disease) accounts for about 8 per 1,000 births and is an important cause of death and disability in infants and children, bringing a heavy burden to families and society. For congenital heart disease, we must combine prevention and treatment. There are three levels of prevention: primary prevention is to find out the risk factors of precocious heart disease, reduce or eliminate these risk factors, and reduce the incidence of precocious heart disease, but we know very little about this, and we cannot prevent precocious heart disease at the root. Secondary prevention is to screen for precocious heart disease during the fetal period (fetal heart ultrasound can be performed after 20 weeks of pregnancy), and for fetuses with serious, uncorrectable precocious heart disease detected, necessary eugenic guidance should be given and pregnancy should be terminated in a timely manner, which is the current focus of prevention and treatment. Tertiary prevention is to improve the treatment effect of children with precocious heart disease, which is highly treatable, has a high cure rate and good long-term effect, and should be diagnosed early and treated at the right time.