If a patient with rheumatologic disease of childbearing age wants to have a baby and wants to keep the disease under control, how do I stop taking medication during the preparation period? How to use medication during pregnancy and breastfeeding? This is the most common clinical problem faced by rheumatologists, because most immunosuppressants have certain toxic side effects and have a certain impact on the development of the baby. However, despite this, there are many immunosuppressants that can be used clinically during the reproductive period.