In principle, the minimum time frame for cold compresses after a muscle strain is 48 hours. In general, most soft tissue injuries can stop bleeding and slow down exudation with frequent and effective cold compresses, but there are special cases. For example, if the patient has abnormal coagulation, the degree of injury is more serious or the soft tissue pressure at the site of the strain is less, many cases need to increase the cold compress time. If the patient has abnormal coagulation function, there is a possibility of gradual and severe swelling symptoms after the strain, and the degree of swelling will increase for a week, then cold compresses should continue to be applied to slow down the bleeding. When the local swelling stops growing or even starts to subside, then convert to hot compress treatment. There are also patients with severe fractures, where the swelling is so severe that it is difficult to stop the bleeding and reduce the swelling with cold compresses alone, and other medications need to be applied to reduce the swelling. Therefore, for minor strains, cold compresses should be applied within 48 hours, and for severe swelling, the decision to stop cold compresses should be made by the performance of the swelling starting to subside.