Acute attacks of chronic pancreatitis can take omeprazole, non-opioid painkillers, levofloxacin and other drugs. 1. Omeprazole: Omeprazole can inhibit the secretion of gastric acid, gastric acid secretion is reduced at the same time the pancreas secretion of pancreatic enzymes is also reduced, reduce the pancreatic enzymes on the pancreas of self-digestion, so as to prevent the pancreatitis condition further aggravation. 2. Non-opioid painkillers, such as ibuprofen and celecoxib, can inhibit the production of prostaglandins and reduce the release of inflammatory mediators, thus alleviating the symptoms of abdominal pain in acute attacks of chronic pancreatitis. 3. Levofloxacin: Inhibit the growth and displacement of bacteria in the intestine and reduce the inflammatory reaction of the intestine, prevent pancreatic infection and prevent the development of severe pancreatitis. 4. enzyme inhibiting drugs: such as growth inhibitors, octreotide, etc., can inhibit pancreatic enzyme secretion, reduce the burden on the pancreas. Patients with acute attacks of chronic pancreatitis should go to the hospital in a timely manner, choose the appropriate medication under the guidance of the doctor, and avoid self-medication at home.