There are many kinds of skin lesions (rashes) occurring in the genital area, these lesions are often not all STDs, but due to the special location of the lesion, the patient’s nervousness and the lack of knowledge of some doctors, they are often misdiagnosed as STDs, resulting in an unnecessary mental burden, so it is recommended to first go to a regular hospital to determine the nature of the lesion, and then to take the appropriate treatment method. Common genital area non-sexually transmitted diseases include: penile pearly papules, sebaceous gland ectasia, non-sexually transmitted warts, fixed drug rash, glans penis, leukoplakia, pseudo-warts of the female genitalia, eczema-like carcinoma, sclerosing lymphadenitis of the penis, sweat duct tumors, verrucous nevus, lymphangiomas, glossy lichen planus, angiokeratoderma, cysts of the penile midline, leukoplakia of the mucous membranes of the vulva, dermatophytosis, vulvar eczema, neuritis, glans penis, psoriasis, flat moss, and so on. Psoriasis, lichen planus, vitiligo, squamous cell carcinoma, Bowen-like papulosis, etc.