It is a chronic inflammatory skin disease of undetermined etiology, characterized by mostly well-defined porcelain-white sclerotic papules and plaques, which may later form white atrophic patches, most often in the female genitalia and male penile foreskin area, but also occurring outside the anal genitalia. The etiology of this disease is unknown, but clinically it is thought to be related to immunology, a small number of people have baldness, vitiligo and thyroid disease; in addition, it is related to genetic factors, endocrine factors and infection. It is mostly seen in women around menopause. Abnormal androgen metabolism may be one of the causative factors in the development of this disease. The disease can be triggered by some stimuli. For example, local trauma, burns. Sclerosing atrophic moss outside the anogenital area and sclerosing atrophic moss of the anogenital area are most commonly seen clinically. The primary lesions outside the genital cry are clustered porcelain or ivory-white papules and plaques with evenly distributed small black-headed acne-like follicular keratoses surrounded by a purplish-red halo. The lesions are initially corn-grain sized or larger flat papules, polygonal, round, oval or irregular in shape, with clear boundaries, glossy white patches, closely spaced but not fused, and later appearing as parchment-like atrophy. The lesions outside of the genital cry are usually found on the upper part of the trunk, but are rare on the palms, soles, scalp and face. The manifestation of genital crypts is more complicated. Sclerosing mosses of the oral cavity are rare. A few genital-anal sclerosing mosses can be complicated by tumors, so patients with this disease in the genital area should be frequently reviewed.