In today’s society, the pressure of life and work, many people often feel chest discomfort, even chest pain, suffocation, many young people are wondering if they have coronary heart disease, in fact, purely by chest discomfort is not diagnosed as coronary heart disease, for young people should be alert to reflux esophagitis. There are many causes of chest discomfort or even pain, the common clinical ones are coronary heart disease and reflux esophagitis, and possibly intercostal neuralgia, but intercostal neuralgia is mostly knife-like pain, more intense, mostly caused by herpes zoster, which is easier to identify. The pathological basis of coronary artery disease is coronary atherosclerosis, which is mostly seen in middle-aged and elderly people over 40 years old, and progresses faster after 49 years old, therefore, the onset of coronary artery disease is mostly in middle-aged and elderly people, mostly accompanied by elevated blood lipids, clinical symptoms of chest discomfort mostly aggravated after physical activity, and ischemic changes in electrocardiogram examination. For young people, reflux esophagitis is often induced by the fast pace of life and work and irregular diet. The pathogenesis of reflux esophagitis is simply that the contents of the stomach (including stomach acid and food) flow back into the esophagus and even the mouth due to damage to the body’s anti-reflux barrier. Clinically, it can manifest as four major types of symptoms. I. Reflux symptoms: acid reflux, regurgitation, regurgitation, belching, obvious after meals, easy to appear in the horizontal position. Second, symptoms caused by reflux stimulating the esophagus: heartburn, chest pain, and difficulty swallowing. This discomfort and pain in the chest is easily associated with coronary heart disease. Third, symptoms of irritation outside the esophagus: cough, asthma, and pharyngitis. Reflux esophagitis induced cough asthma may be the first symptom of patients, which should be taken seriously. Fourth, foreign body sensation in the pharynx. The diagnosis of reflux esophagitis is based on three points: obvious reflux symptoms, endoscopic evidence of reflux esophagitis, and objective evidence of excessive acid reflux in the esophagus. The treatment of reflux esophagitis I would like to talk about in terms of both Western medicine and Chinese medicine. The general treatment is similar in both, requiring the patient to avoid eating within 2 hours before bedtime, not to lie down immediately after eating, avoid high fat, chocolate, coffee, strong tea, and to quit smoking and alcohol. Western medicine medication is used to improve the peristaltic function of the esophagus and promote gastric emptying with pro-gastric motility drugs, such as mosapride and cisapride. Acid suppressants, such as cimetidine, famotidine, pantoprazole, rabeprazole, etc., are used to inhibit gastric acid and reduce the stimulation of gastric acid on the esophagus. Surgical treatment is performed by fundoplication to stop the regurgitation of gastric contents into the esophagus. However, there are strict indications for surgery and the procedure is more tedious.