Most patients with PCOS often consult with obesity, abnormal menstruation, acne, and acanthosis nigricans after puberty onset. Because the main clinical manifestations of PCOS are very similar to the physiological changes of puberty, and the diversity and heterogeneity of symptoms and signs, the diagnosis of PCOS often lags behind. First, the health management of obese girls, pubertal PCOS and distant harm scientific knowledge propaganda and education In view of the morbidity characteristics of adolescent PCOS, maternal perinatal and perinatal health care as well as the health management of obese girls should be done, promote correct and good health, nutrition, diet concept and life style; strengthen the obese children, metabolic syndrome, pubertal PCOS and distant harm scientific knowledge propaganda and Education and lifestyle intervention. Screening for high-risk groups Screening for PCOS for adolescents with irregular menstruation 2-3 years after menarche who have the following risk factors for PCOS: 1. family history (PCOS, male pattern baldness, diabetes, hypertension, obesity); 2. pre-pubertal obesity (weight over 20% of standard weight); 3. restricted growth during fetal life, rapid growth after birth or excessive birth weight; ( IUGR, gigantism, etc.) 4. early onset of adrenocortical function or early appearance of pubic hair; 5. early menarche (before age 10) or precocious puberty; 6. overweight or obesity; 7. persistent anovulation; 8. hyperandrogenemia; 9. metabolic syndrome (diagnostic criteria developed at the 2003 American Fertility Society Rotterdam meeting); 10. hyperinsulinemia in different disease conditions; clinicians need to Educate the screened girls and their parents about the disease and closely follow up the girls throughout their adolescence; some patients with PCOS develop a distinctly “PCOS-like” appearance at an early age. Early identification of girls at risk for PCOS and early monitoring and treatment of PCOS at an early stage of development may be the most effective way to prevent the development of PCOS and the long-term complications of PCOS.