Massive alveoli, defined as large alveoli affecting ≥1/3 of one or both hemithorax, can severely disrupt pulmonary function in the involved lung and even invade other lungs; resection can provide significant relief and improve pulmonary function. In general, resection is most beneficial in patients with large alveoli affecting >1/3 of the hemithorax and with FEV1 only about half of the normal expected value. The degree of improvement in lung function is related to the amount of normal or slightly diseased lung tissue that is compressed by the large alveoli being removed. Serial chest X-rays and CT can clarify whether the patient’s functional status is due to alveolar compression or to generalized emphysema. Rarely, large alveoli can be affected by septic pathogens, such as Aspergillus. Septic infections should be treated with appropriate antibiotics. Giant pulmonary alveoli are easily misdiagnosed as limited pneumothorax by lower hospitals, and closed drainage is performed. Some patients will have increased symptoms, and temporary relief can be obtained in local tension giant pulmonary alveoli, but then they will continue to have respiratory distress and co-infection, therefore, giant pulmonary alveoli, should be clearly recognized to avoid misplaced drainage. Treatment: 1. Adequate preoperative physical examination, and follow-up history, long-term chronic obstructive pulmonary and recurrent infection cases, should be strictly surgical indications and preoperative preparation, asthma, sputum, anti-inflammatory, simple pulmonary function evaluation, blood gas analysis when necessary, check oxygenation function. Such patients are not suitable for pulmonary function testing; 2, multiple, bilateral, difficult to withstand surgery, difficult to completely resect patients, has been a tangled selection of cases of such diseases, bilateral can be completely resected, split-side surgery, the safety factor is higher than the same period of surgery 3, unilateral can be completely resected, the efficacy is remarkable Case sharing: with a county in Heze completed a case of giant type of pulmonary blister occupying almost all of the right side of the chest cavity, 20-year-old boy The right thoracic cavity was already tensionally expanded, and the operation was completed with a minimally invasive small incision of 6 cm, with good postoperative recovery. Thorax right side tensional expansion 6cm minimally invasive small incision to complete the surgery, intraoperative see the thoracic cavity is huge occupy the right side of the chest cavity 85% herpes occupy the resected giant pulmonary herpes, see scale.