Rough and dry skin may be due to medication, inflammation of the skin, metabolism, or damage to the skin’s epidermis due to human factors. In this case, it is usually necessary to try to restore the skin’s moisturizing state, which can usually be improved by using topical moisturizing creams. Usually you can use vitamin E cream or 10% urea cream, sometimes you can also use mucopolysaccharide polysulfate cream for topical application if it is limited, or you can use sodium heparin cream.