1. Female lupus patients with normal fertility should practice family planning. 2. The best time to arrange pregnancy is during the lupus quiescent phase, although there is no guarantee that the disease will remain in quiescence thereafter. It should be emphasized that even if pregnancy occurs after 5-6 months of quiescence, there are still about 10% of patients with lupus flare-ups. 3. The possibility of disease flare-ups is related to the severity of the disease; the milder the disease, the less likely it is to flare up. Doctors must master the indications for preserving pregnancy in patients with SLE. 4. Pregnancy during active disease, especially in patients with lupus nephritis, is prone to hypertension or prenatal eclampsia. 5. Women with antiphospholipid antibodies have a high rate of miscarriage, and should be treated with long-term low-dose aspirin, or heparin and prednisone, and Chinese herbal medicine. 6. The entire pregnancy and puerperium should be closely monitored and actively treated. Patients should be followed up regularly at the SLE specialist clinic and obstetrics clinic at the same time. 7. Doctors must pay attention to the activity level of SLE disease, pregnancy complications and fetal development, and pay attention to the presence of stillbirth. Regularly check blood and urine routine, blood sedimentation, C-reactive protein, complement, and immunological examination if necessary. If the patient’s clinical symptoms and laboratory indicators suggest that the patient’s condition tends to worsen, the patient should be advised to terminate the pregnancy as soon as possible. 8. Caesarean section should be performed if there are the following indications, such as maternal aseptic hip necrosis, prenatal eclampsia, fetal distress, cephalopelvic disproportion, transverse fetal position, etc. 9. Patients with SLE in labor should be admitted to the obstetrical ward early to strengthen the observation of the disease and increase the dosage of hormones appropriately during the delivery period to avoid deterioration of the disease due to excessive fatigue during delivery. The preterm birth rate of patients with active disease is as high as 60%, and 30% of them have intrauterine growth retardation, so attention should be paid to the monitoring of newborns. 11. 1% of infants born alive to lupus patients suffer from congenital heart block, and infants of pregnant women with anti-RO/SSA and/or anti-LA/SSB positivity are more prone to congenital heart block, with an incidence of up to 8.8%, which should be taken seriously. 12, taking prednisone generally does not cause congenital malformations, but taking cytotoxic drugs in early pregnancy has the risk of causing congenital malformations, so avoid giving immunosuppressive drugs. With the continuous progress of modern medicine, early diagnosis and systematic and regular treatment, the survival rate of patients with SLE has been greatly improved. Similarly, with increased awareness of the various potential problems of the mother and fetus, and with aggressive treatment and guidance, most lupus patients will have the opportunity to enjoy the joys of motherhood.