Married female patients with SLE who have fertility requirements, conditions for fertility and pregnancy: 1. No drugs affecting pregnancy, such as methotrexate; 2. Prednisone dose ≤ 10 mg, without methylprednisone tablets (prednisone does not pass the placental barrier, while methylprednisone); 3. No impairment of organ function; 4. Normal indicators; 5. Stable disease for more than 1 year. Meet the above conditions, but also must meet: 1, but also in line with the national pregnancy policy! 2.After pregnancy, we must visit the obstetrics and rheumatology department for regular monthly follow-up.