Denogestrel tablets have the effect of treating adenomyosis, which can inhibit the progression of adenomyosis by lowering the level of estrogen. They are more effective for light adenomyosis, but less effective for more severe adenomyosis, for which surgery is recommended. Adenomyosis is a common gynecological condition in which the endometrial glands and mesenchyme invade the myometrium, affecting the normal function of the endometrium and causing abnormal menstrual cycles, dysmenorrhea, heavy menstruation, and even infertility in patients. It may usually be associated with uterine damage, hyperestrogenemia and hyperprolactinemia, and reproductive tract obstruction. Denogestrel tablets, a progestin-like drug, can improve the pain symptoms of adenomyosis patients by appropriately lowering gonadotropin secretion and thus estrogen levels in patients through negative feedback regulation. Through the medication of Denogestrel Tablets, it can improve the excessive menstruation, raise the patient’s hemoglobin level and limit the progress of adenomyosis. Side effects such as irregular vaginal bleeding, constipation and nausea are likely to occur with the use of Denogestrel Tablets, so they should be used under the guidance of a physician. For adenomyosis, surgery with medications that suppress the endometrium is usually used.