In most cases, endometritis can’t get better if you only take doxycycline hydrochloride, and the chances of getting better are higher if you combine it with other antibiotic drugs. The common pathogens of endometritis are Chlamydia, Neisseria gonorrhoeae, Mycoplasma, in addition to aerobic bacteria, anaerobic bacteria or a mixture of two kinds of bacteria, and these two kinds of pathogens are divided into gram-negative and gram-positive, so most of the cases of endometritis are combined with several kinds of broad-spectrum antibiotic drugs together for treatment. Doxycycline hydrochloride is more effective for mycoplasma infection and chlamydia infection, but is not sensitive to other pathogenic bacteria, if you just take doxycycline hydrochloride, this situation is generally not very effective treatment. If doxycycline hydrochloride combined with cephalosporin and metronidazole drugs together, so as to target a variety of pathogenic bacteria, the effect will be more obvious. Doxycycline hydrochloride may have adverse reactions, such as nausea, vomiting, abdominal pain, erythema, papules, etc. It is prohibited for women with fatty liver degeneration or during pregnancy, and may cause hepatotoxicity or pancreatitis. Therefore, with endometritis do not use drugs privately, you should go to the hospital for examination, according to the condition of the choice of medication, to avoid delay or cause adverse reactions.