Pancreatic atrophy in diabetic patients should first clarify the cause of the disease and then treat the cause. Pancreatic atrophy may be due to diabetes, chronic pancreatitis, etc. If it is caused by diabetes, it can be controlled by adopting a diabetic diet, controlling blood glucose, taking oral medication, etc. It is recommended to consult a doctor. Diabetic patients should adopt diabetic diet, oral hypoglycemic drugs to control blood glucose within the normal range, the use of insulin dose should be individualized, the blood glucose control, can delay the pancreas further atrophy. Chronic pancreatitis patients should quit smoking, alcohol; small meals, high protein, high vitamin, low fat diet, control sugar intake; indigestion, especially for steatorrhea patients, should be given a large number of exogenous pancreatic enzyme preparations; if necessary, insulin replacement therapy. Note that the above drugs should be used under the guidance of a doctor, avoid unauthorized use of drugs, so as not to cause adverse effects. If diabetic patients have pancreatic atrophy, it is recommended to consult a doctor in a timely manner, improve the relevant examination, clarify the cause of the disease, and target treatment.