Hepatoblastoma has not found a clear genetic test. Hepatoblastoma is diagnosed by serum alpha-fetoprotein level test, infectious virus test, imaging test and pathology test. 1. Serum alpha-fetoprotein level test: also known as AFP level test, most patients have abnormally elevated serum AFP level, and the degree of elevation is related to the disease. 2. Virus infection test: mainly to detect whether the child has been infected with hepatitis B virus, if infected, the risk of hepatoblastoma is increased. 3. Diagnosis through imaging to diagnose the structure, size, nature of the mass and its relationship with the surrounding tissues. 4. Pathological examination: Pathological examination is the basis of definitive diagnosis of hepatoblastoma, which can stage and classify the disease. At present, the genetic test of hepatoblastoma is still in the exploratory stage, and the test method is still unclear, so it is recommended to go to specialized hospitals for relevant examination.