With the improvement of prenatal screening technology, more and more fetuses with various congenital diseases can be diagnosed prenatally. A significant number of these sick newborns need to be treated first after birth, such as congenital esophageal atresia, congenital intestinal atresia, congenital anal atresia, fetal fecal peritonitis, etc., otherwise various complications will occur and lead to the loss of life. In view of this situation, in addition to minimizing the attack of various teratogenic factors and improving pregnancy checkups, how to choose a treatment plan when the fetus is examined for possible digestive tract malformations in the second trimester becomes a real problem. Because newborns with birth defects may have a poor prognosis due to vomiting, misaspiration, neonatal pneumonia, hypothermia, infection and other adverse effects, so reducing transport and timely treatment can minimize the risk, so for such patients, we recommend choosing a general hospital with comprehensive treatment capabilities, and transferring the child to a neonatal care unit as soon as possible after delivery in the obstetrics department, and combining medical and surgical procedures for We recommend to choose a general hospital with comprehensive treatment capability. At present, our hospital has successfully treated dozens of patients with gastrointestinal anomalies with this seamless one-stop treatment.