Vaginal cancer is a malignant tumor that grows in the vagina and can be divided into primary and secondary vaginal cancer depending on the nature of the tumor. Primary vaginal cancer is a malignant tumor that grows in the vagina itself, but it is still relatively rare and is usually squamous epithelial cancer. Secondary vaginal cancer is mainly due to metastases from malignant tumors of the cervix, vulva, endometrium, and rectum. Because the vaginal wall itself is very thin and lymphatic distribution is very rich, the cancer develops very fast. Moreover, it is connected with the bladder and rectum, so it is easy to be accumulated by malignant tumors from other parts. The clinical symptoms of vaginal cancer are also obvious, such as irregular vaginal bleeding, abnormal menstruation, bleeding during sexual intercourse, postmenopausal bleeding, watery or bloody vaginal discharge with foul odor and a series of clinical symptoms. Moreover, localized lesions in the vagina are mostly papillary or cauliflower-shaped, followed by ulcerated lesions. In the advanced stage of vaginal cancer, frequent urination, blood in urine, painful urination, anal swelling, blood in stool, vaginal pain, and even vesico-vaginal fistula or recto-vaginal fistula may also occur. Vaginal cancer is caused by many factors, so once women find abnormalities in the vagina, they should seek medical help in time.