Parkinson’s disease is also known as “tremor palsy”. It was first described systematically in 1817 by the English physician James Parkinson. Parkinson’s disease is a degenerative disease of the central nervous system common in middle and old age, the fourth most common neurodegenerative disease, affecting 1% of people aged ≥65 years and 0.4% of people aged >40 years. Parkinson’s disease mostly develops after the age of 50, and 50% to 80% of cases are insidious, mainly manifesting as tremor, slow movements, muscle tonus, and abnormal posture and gait. The first symptom is usually a resting “pill-twisting” tremor of 4-6 Hz in one hand. The tremor is most pronounced when the limb is at rest, decreases when the limb is performing activities, and disappears during sleep; emotional stress or fatigue can aggravate the tremor, which is usually most severe in both hands, arms and legs, and the order of symptoms is also earliest in the hands and latest in the legs, while tremor can also occur in the jaw, tongue, forehead and eyelids, but vocalization is not affected. Myotonicity, some patients only show rigidity, no tremor, and progressive rigidity plus. In bradykinesia, the patient’s movements become slower and slower (slow movements), with fewer and more difficult movements, which can be manifested in the face as a mask face: rigidity combined with too few movements leads to an expressionless face, with the mouth often open and fewer blinks. Hypermobility combined with impaired control of distal muscles can lead to micrographia. The patient finds it difficult to open the gait; the gait is sluggish, the gait distance is reduced, both upper limbs are in a fixed flexed position at the waist, and there is no natural swing of both upper limbs during walking. The gait may appear to be unintentionally accelerated, and the patient may turn to running to avoid falling, with a panicked gait (festination). In addition to the motor symptoms mentioned above, there are also non-motor symptoms, including cognitive dysfunction, depression, and postural hypotension.