The average nighttime blood pressure in normal subjects is about 15% lower than the average daytime blood pressure, and the difference between the average nighttime blood pressure and the average daytime blood pressure in hypertensive patients <10% is called non-scooped (non-dipping) hypertension, which is one of the strongest risk factors for adverse cardiovascular events in hypertensive patients. Most patients with CKD have non-scooped blood pressure and are at high risk for progression of renal function and death in patients with CKD. Adapting at least one antihypertensive medication to bedtime may help to regulate the blood pressure rhythm and change non-spooning to spooning blood pressure, thus potentially improving prognosis.