Can people with rheumatic diseases get vaccinated? This is a difficult question that is asked every day. In fact, the question is two-way: can vaccination cause rheumatism? Professor Tian has given a good answer to both questions. I admire Professor Tian’s style of research that is clinically relevant. Influenza vaccine is not recommended for patients with systemic lupus erythematosus who have active disease or use immunosuppressive drugs. Patients with rheumatoid arthritis, active disease, immunosuppressant use, and susceptible genetic background should be used with caution. Hepatitis B vaccine Hepatitis B vaccine is safe for patients with stable SLE. Pneumococcal vaccine is safe for patients with rheumatic diseases. Summary: 1. Vaccination is safe, and although there is some correlation with rheumatic diseases, the onset is rare. 2. The overall safety of vaccination for patients with rheumatic diseases is good. 3. Live vaccination is not recommended for patients with rheumatic diseases 4. Patients with rheumatic diseases have a reduced immune response to vaccines, but it is still a cost-effective protective measure. 5.Patients with stable disease and not using immunosuppressants can be vaccinated. 6.Patients who use biological agents, the time of vaccination is related to the protective effect. (Vaccination on the day of using a biological agent produces antibody levels no different from those using conventional immunosuppression; if vaccination is given 3 weeks after using a biological agent, the response to produce antibodies is significantly lower.)