Multidrug-resistant tuberculosis is one of the more difficult types of tuberculosis, mainly referring to the infection of the body with Mycobacterium tuberculosis, which has developed resistance to common anti-tuberculosis drugs. Patients with multidrug-resistant tuberculosis have the possibility of eradication if they choose the right drugs and have a sufficient course of treatment, but the treatment time is longer and the requirements for patients are higher, so they need to do the following: 1. The doctor needs to know the effect of anti-tuberculosis treatment and adjust the treatment plan when necessary; 3. Strictly follow the doctor’s prescription: Due to the difficulty of treating multidrug-resistant tuberculosis, the choice of drugs has certain limitations, and the second-line drug treatment is generally the main treatment. Once more drug resistance occurs, the treatment difficulty will be further increased and the disease will be aggravated, resulting in prolonged illness; 4, close monitoring: the incidence of adverse reactions to second-line anti-tuberculosis drugs has increased compared with first-line anti-tuberculosis drugs, and should be closely monitored for adverse reactions. If adverse reactions occur, they need to be reflected to the doctor in time to avoid aggravation of the disease.