Generally the chicken essence on the market are in line with national safety standards, moderate consumption does not have a serious impact on the human body. However, when consumed in large quantities, it can have adverse effects on people with cardiovascular and cerebrovascular diseases and kidney diseases. It also has a negative impact on middle-aged and elderly people with osteoporosis, obese people and children.1. Aggravating the burden on the organs: The main components of chicken essence include MSG, edible salt, rice, sugar, sodium nucleotide salt, edible flavor, chicken, etc. Because it contains a large amount of sodium, too much consumption may aggravate edema for people prone to edema such as cardiovascular and kidney diseases. At the same time, the sodium in chicken essence needs to be excreted through the kidneys, the intake of more will increase the burden on the kidneys, especially for people with kidney dysfunction is more unfavorable; 2, affect the bones: a large number of chicken essence consumption, the level of sodium in the body may increase, so it is easy to cause calcium loss, for children in bone development, as well as the occurrence of osteoporosis in the middle-aged and elderly groups will have a certain negative impact; 3. Zinc deficiency: too much chicken essence consumption will lead to an increase in the blood glutamate content, affecting the body’s metabolism, resulting in zinc deficiency. In addition, chicken essence is a condiment, excessive consumption of chicken essence can improve appetite, but there is an increased risk of obesity, affecting neurological function. Therefore, when consuming chicken essence should pay attention to the appropriate amount, but it is recommended that we eat a light diet on a daily basis and minimize the excessive intake of condiments such as MSG and salt to avoid certain damage to the organism.