Zinc deficiency 1, zinc-containing foods: beef, breast milk, oysters 2, the function of zinc: (1) is more than 50 kinds of metabolic enzymes and coenzymes components, in the nucleic acid and protein metabolism plays an important role taste, gastrointestinal tract function (2) loss repair, growth and development (3) immune function, reproductive function (4) vitamin A utilization disorders, showing symptoms of vitamin A deficiency such as night blindness 3, the basic concept: the system Long-term deficiency causes loss of appetite, ringworm, growth retardation, dermatitis as the main manifestation [Etiology]: 1, insufficient intake as the main cause of deficiency (1) animal food is rich in zinc and easily absorbed; plant food contains phytic acid and fiber, which affects the absorption of zinc, so long-term lack of animal food may lead to zinc deficiency in the body. (2) Failure to add zinc-rich animal food supplements at the right time (3) Partial and picky eating in older children (insufficient animal protein in the diet) 2. Relative increase in need Period of rapid growth and development, recovery from malnutrition, post-surgery, acute infectious diseases, etc. 3. Increase in loss Trauma, starvation: disease states such as diabetes, chronic kidney disease, etc. 4. Genetic factors Enteropathic acrodermatitis is due to autosomal The disease of recessive inheritance, the affected children’s small intestine』diphtheric mucosal cells have low capacity for zinc aggregation, which reduces the absorption of zinc and leads to the occurrence of zinc deficiency. Clinical manifestations: 1. susceptibility to infections: mycobacterial infections 2. recurrent oral ulcers, slow wound healing: (common in early stages of zinc deficiency) 3. loss of appetite, abnormal taste sensation, heterophagia: (common in early stages of zinc deficiency) 4. growth stagnation, short stature: (chronic deficiency) 5. reduced dark adaptability: 6. skin inflammation, peeling: acute zinc deficient children may have nail fungus, peeling, rough skin, pigmentation extremities and mouth, anus, genitalia 7. delayed sexual development: (long-term deficiency) 8. delayed intellectual development: (long-term deficiency) 9. possible congenital malformations: maternal zinc deficiency – fetal stunting, premature birth, low birth weight [prevention] 1. pregnant women zinc supplementation 2. breastfeeding 3. reasonable addition of complementary foods 4. no picky eating and no partial eating [treatment] 1. 1.Remove the cause of the disease 2.Treat with zinc supplementation Preparation: 1% zinc sulfate solution, zinc gluconate, zinc acetate. Note: Protein intake should be increased (replenishment of calories, protein and other nutrients is conducive to the correction of zinc deficiency), and attention should be paid to the treatment of iron deficiency anemia.